Imatinib

Active Ingredient: Imatinib
Form: Oral tablet
Brand Name: Glivec
Generic Name: Imakin
Generic Manufacturer: Ziska Pharmaceuticals

Indications:
Glivec is indicated for the treatment of Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML) in chronic, accelerated, or blast phase; Ph+ acute lymphoblastic leukemia (ALL); myelodysplastic/myeloproliferative diseases associated with PDGFR gene rearrangements; aggressive systemic mastocytosis; hypereosinophilic syndrome/chronic eosinophilic leukemia; and locally recurrent or metastatic dermatofibrosarcoma protuberans (DFSP).

Dosage and Administration:
The recommended dose for adult patients with chronic phase CML is 400 mg daily (some cases may require 600–800 mg in divided doses). For ALL and other indications, the dose should be adjusted based on clinical condition. All doses should be taken with food and a large glass of water. Tablets can be dissolved in water or juice for patients with swallowing difficulties.

Common Side Effects:
Fluid retention, edema, hematologic toxicity, congestive heart failure, hepatotoxicity, bleeding, gastrointestinal discomfort, and hypothyroidism.

Storage:
Store below 30°C in a cool, dry place away from light. Keep out of reach of children.

Frequently Asked Questions

Q: What is the relationship between Glivec and Imatinib?
A: Glivec is the brand name registered by the original manufacturer. Imatinib is its active ingredient.

Q: Is the Glivec sold by Mediva Rx the original brand-name drug?
A: No. Mediva Rx offers a high-quality generic version manufactured by one of Bangladesh’s top 10 pharmaceutical companies. It contains the same active ingredient and therapeutic efficacy as the original, and is tested and approved by the Directorate General of Drug Administration (DGDA).

Q: Is the manufacturer of this generic version reliable?
A: Yes. We work with Ziska Pharmaceuticals, a leading pharmaceutical company in Bangladesh with in-house R&D, manufacturing, and quality control laboratories. They are internationally certified for Good Manufacturing Practice (GMP). You can purchase with confidence.

Disclaimer:
This information is for reference only. Treatment decisions should follow your physician’s advice and be based on the official medication guide and the latest clinical evidence.

Drug Instructions (Package Insert):
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