Asciminib

Active Ingredient: Asciminib
Form: Capsule
Brand Name: Scemblix
Generic Name: Ascentib
Generic Manufacturer: Ziska Pharmaceuticals

Indications:
Scemblix is indicated for the treatment of Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML) in patients who have previously received two or more tyrosine kinase inhibitors, or for those with the T315I mutation.

Dosage and Administration:
The recommended dose for CML patients is 80 mg once daily (or 40 mg twice daily), and may be adjusted to 200 mg per day in two divided doses depending on the clinical situation. It must be taken on an empty stomach—no food 2 hours before and 1 hour after dosing. If a dose is missed, do not make it up. Dose reductions may be considered for patients with severe adverse reactions.

Common Side Effects:
Bone marrow suppression, pancreatic toxicity, hypertension, allergic reactions, and cardiovascular toxicity.

Storage:
Store below 25°C in a cool, dry place away from light and out of reach of children.

Frequently Asked Questions

Q: What is the relationship between Scemblix and Asciminib?
A: Scemblix is the brand name registered by the original manufacturer. Asciminib is its active ingredient.

Q: Is the Scemblix sold by Mediva Rx the original brand-name drug?
A: No. Mediva Rx offers a high-quality generic version produced by one of Bangladesh’s top 10 pharmaceutical manufacturers. It contains the same active ingredient and efficacy as the original, tested and approved by the Directorate General of Drug Administration (DGDA).

Q: Is the manufacturer of this generic version reliable?
A: Yes. Ziska Pharmaceuticals is a leading Bangladeshi drugmaker with its own R&D, production, and quality control facilities, and is certified for international pharmaceutical manufacturing standards. You can purchase with confidence.

Disclaimer:
This information is for reference only. Treatment decisions should follow your doctor’s advice and be based on the medication guide and latest research.

Drug Instructions (Package Insert):
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